Urology Clinical Briefs

• Long-Term Use of Trimethoprim-Sulfamethoxazole May Reduce UTIs in At-Risk Children CME In a randomized trial, long-term, low-dose trimethoprim-sulfamethoxazole shows a consistent but modest treatment effect across subgroups of children with urinary tract infections.
  Medscape Medical News CME, November 2009
• FDA Safety Changes: DepoDur, Neoral, Lexiva CME/CE The FDA has approved safety labeling revisions for morphine sulfate extended-release liposome injection, cyclosporine capsules and oral solution, and fosamprenavir calcium tablets and oral suspension.
  Medscape Medical News CME, November 2009
• Depression in Older Cancer Patients Responds Better to Collaborative Program CME A collaborative program headed by a depression care manager, which included a structured psychotherapy program, was better than usual care in older cancer patients with depression.
  Medscape Medical News CME, November 2009
• Higher-Intensity Continuous Renal Replacement May Not Reduce Mortality Risk From Acute Kidney Injury CME In a randomized controlled trial in critically ill patients with acute kidney injury, treatment with higher-intensity continuous renal replacement therapy did not reduce mortality rate at 90 days.
  Medscape Medical News CME, November 2009
• Intensified Blood Pressure Control May Improve Renal Function in Children With CKD CME In a randomized trial, intensified blood pressure control targeting 24-hour blood-pressure levels in the low range of normal was associated with a substantial benefit in renal function.
  Medscape Medical News CME, November 2009
• FDA Approvals: Elitek, Fluarix, Votrient CME/CE The FDA has approved an expanded indication for rasburicase intravenous infusion, a pediatric use of a trivalent inactivated influenza vaccine, and pazopanib tablets for advanced renal cell carcinoma.
  Medscape Medical News CME, October 2009
• Psychiatric Disorders, Sexual Trauma Linked to Urinary Tract Symptoms CME Depression, anxiety, and sexual trauma have all been implicated as risk factors in lower urinary tract symptoms.
  Medscape Medical News CME, October 2009
• Serum, Cerebrospinal Fluid Urate May Predict Clinical Decline in Parkinson's Disease CME In a Parkinson's disease study, higher baseline concentrations of serum and cerebrospinal fluid urate were associated with slower rates of clinical progression.
  Medscape Medical News CME, October 2009
• Bladder Cancer Management Reviewed CME A review for primary care clinicians suggests best practices for the diagnosis and treatment of bladder cancer.
  Medscape Medical News CME, October 2009
• FDA Approvals: Gardasil, Cervarix, Micardis CME/CE The FDA has approved a vaccine for the prevention of genital warts in males, a human papillomavirus vaccine for cervical cancer prevention, and an expanded indication for telmisartan.
  Medscape Medical News CME, October 2009
• ACP Issues Guidelines for Treatment of Erectile Dysfunction CME Unless there is a contraindication such as nitrate therapy, the American College of Physicians strongly recommends therapy with an oral phosphodiesterase type 5 inhibitor for erectile dysfunction.
  Medscape Medical News CME, October 2009
• Lack of Exercise Linked to Increased Mortality in Chronic Kidney Disease CME Based on findings from this observational study, increased physical activity might have a survival benefit in patients with chronic kidney disease as well as in those without chronic kidney disease.
  Medscape Medical News CME, October 2009
• Minimally Invasive Synthetic Suburethral Sling Operations May Be Effective CME A systematic review suggests that these procedures are as effective for stress urinary incontinence as more invasive procedures but with fewer postoperative complications.
  Medscape Medical News CME, October 2009
• Dialysis Linked to Functional Decline in Nursing Home Residents With End-Stage Renal Disease CME In an uncontrolled study of nursing home residents with end-stage renal disease, dialysis initiation was associated with a substantial and sustained decline in functional status.
  Medscape Medical News CME, October 2009
• ACEIs More Likely Than Other Antihypertensive Drugs to Cause Hyperkalemia; Overall Risk Low in Nondiabetic Kidney Disease CME However, in nondiabetic patients with hypertensive chronic kidney disease treated with angiotensin-converting enzyme inhibitors, the risk for hyperkalemia is small.
  Medscape Medical News CME, October 2009
• Weight Loss May Help Preserve Renal Function in Obese Patients With Kidney Disease CME A systematic review and meta-analysis shows that weight loss achieved by diet and exercise is associated with decreased proteinuria and could prevent additional decline in kidney function.
  Medscape Medical News CME, September 2009
• Unenhanced CT May Assist in Diagnosis of Children With Flank Pain CME In a retrospective study, unenhanced computed tomography played an important role in evaluating children with flank pain; approximately 15% of children with urolithiasis did not have hematuria.
  Medscape Medical News CME, September 2009
• Patients With CKD Should Be Screened Routinely for Depression CME A study shows that 1 in 5 patients with chronic kidney disease have a major depressive episode and that depression is independently associated with poor outcomes in patients receiving dialysis.
  Medscape Medical News CME, September 2009
• Laparoscopic Uterosacral Nerve Ablation May Not Be Helpful for Women With Chronic Pelvic Pain CME Compared with laparoscopy without pelvic denervation, laparoscopic uterosacral nerve ablation did not improve pain, dysmenorrhea, dyspareunia, or quality of life in women with chronic pelvic pain.
  Medscape Medical News CME, September 2009
• Oral Contraceptives Lower Risk of Urinary Incontinence Symptoms CME Women of child-bearing age who use oral contraceptives face a lower risk for lower urinary tract dysfunction than women of similar ages who do not, say researchers from Sweden.
  Reuters Health Information CME, September 2009