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Marrying Rheumatoid Arthritis Pathophysiology to Treatment Mechanism of Action: A Focus on New Therapies CME/CE Author Information and Disclosures Release Date: April 30, 2008; Valid for credit through April 30, 2009 | Physicians - maximum of 0.5 AMA PRA Category 1 Credit(s)™ for physicians; Nurses - 0.5 nursing contact hours (0.5 contact hours in the area of pharmacology) |  | To participate in this internet activity: (1) review the target audience, learning objectives, and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation; (4) view/print certificate View details. Contents of This CME/CE Activity Legal DisclaimerThe material presented here does not necessarily reflect the views of Medscape or companies that support educational programming on www.medscape.com. These materials may discuss therapeutic products that have not been approved by the US Food and Drug Administration and off-label uses of approved products. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or employing any therapies described in this educational activity. Copyright © 2008 Medscape. |
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Learning Objectives Upon completion of this activity, participants will be able to: - Review the current understanding about the pathophysiology of rheumatoid diseases
- Discuss the immunopathology of rheumatoid arthritis (RA) and its relevance to the development of novel biologic therapies
- Examine the
inflammatory cascade, the role of cytokines, and specifically the role of interleukin (IL)-6 and the pleiotropic nature of its effects
- Discuss systemic manifestations associated with RA, including anemia, depression, sleep disturbances, and fatigue, and their effects on patient outcomes
Authors and Disclosures Vibeke Strand, MD, FACP
Disclosure: Vibeke Strand, MD, FACP, has disclosed that she has served as a consultant for Abbott Immunology, Allergan, Almirall, Amgen Corporation, AstraZeneca, Bayhill, Bexel, Biogen Idec, CanFite, Centocor, Chelsea, Cypress Bioscience, Inc., Dainippon Sumitomo, FibroGen, Forest Laboratories, Genelabs, Genentech, Human Genome Sciences, Incyte, Jazz Pharmaceuticals, Lexicon Genetics, Lux Biosciences, Novartis Pharmaceuticals, Novo Nordisk, NOXXON Pharma, Ono
Pharmaceuticals, Pfizer, Procter & Gamble, Proprius, Rigel, Roche, sanofi-aventis, Schering-Plough, Serono, SKK, UCB, VLST, Wyeth-Ayerst, XDx, and Zelos Therapeutics. Dr. Strand has also disclosed that she has served on the advisory board for Abbott, Amgen, Biogen Idec, Bristol-Myers Squibb, CanFite, Centocor, Chelsea, Novartis, Pfizer, Roche, Schering-Plough, and UCB. Dr. Strand has also disclosed that she has served on the speaker's bureau for Abbott, Amgen, Centocor, and
Pfizer. Robert A. Terkeltaub, MD Disclosure: Robert A. Terkeltaub, MD, has disclosed that he has received a grant for clinical research from TAP. Dr. Terkeltaub has also disclosed that he has served as an advisor or consultant to TAP, Regeneron, Savient, and Novartis. Arthur Kavanaugh, MD Disclosure: Arthur Kavanaugh, MD, has disclosed that he has received
grants for clinical research from Bristol-Myers Squibb, Genentech, Abbott Pharmaceuticals, Amgen, and Centocor. Helen Fosam, PhD Disclosure: Helen Fosam, PhD, has disclosed no relevant financial relationships. Jayashree Gokhale, PhD Disclosure: Jayashree Gokhale, PhD, has disclosed no relevant financial relationships.
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Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Medscape, LLC designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity.
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This Activity is sponsored by Medscape Continuing Education Provider Unit. Medscape is an approved provider of continuing nursing education by the New York State Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation.
Awarded 0.5 contact hour(s) of continuing nursing education for RNs and APNs; 0.5 contact hours are in the area of pharmacology. Provider Number: 6FDKKC-PRV-05
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